Address
McGill University Health Centre
Montreal General Hospital
1650 Cedar Avenue
Montreal Quebec H3G 1A4
Canada
User Profile
Disciplines Trained In: Biochemistry, Cardiology, Genetics, Internal Medicine
Research Disciplines: Cardiology, Genetics, Internal Medicine
Areas of Research: Cardiovascular Diseases, Genetic Diseases, Health Prevention, Hypertension, Lipid Disorders, Metabolic Diseases
Fields of Application: Biomedical Aspects of Human Health
Research Specialization Keywords: Cardiometabolic Health, Cardiovascular Epidemiology, Cardiovascular Prevention, Cholesterol, Coronary Artery Disease, Familial Hypercholesterolemia, Genetics, Hypertension, Lipids, Vascular Health
2021/9 – 2022/12 Post-doctorate, Beedie Fellowship in Cardiovascular Disease Prevention, Cardiometabolic
Health and Lipidology, University of British Columbia
Degree Status: Completed
2021/7 – 2021/8 Post-doctorate, Program in Clinical Effectiveness, Harvard Medical School
Degree Status: Completed
2019/7 – 2021/7 Post-doctorate, General Internal Medicine, Residency Subspeciality, McGill University
Health Centre
Degree Status: Completed
2016/7 – 2019/7 Post-doctorate, Internal Medicine, Residency Core, McGill University Health Centre
Degree Status: Completed
2012/6 – 2016/6 Doctorate, Doctor of Medicine (M.D.), Université Laval
Degree Status: Completed
2008/9 – 2013/2 Doctorate, Doctor of Philosophy (Ph.D.), Cardiovascular Biochemistry, McGill University
Degree Status: Completed
Transferred to PhD without completing Masters?: No
2006/8 – 2008/8 Master’s Thesis, Master of Science (M.Sc.), Biochemistry and Human Genetics, McGill
University
Degree Status: Completed
2003/8 – 2006/5 Bachelor’s, Bachelor of Science (B.Sc.), Biochemistry, McGill University
Degree Status: Completed
2001/8 – 2003/5 Diploma, Diploma Collegial Studies (D.E.C.), Health Science, Marianopolis College
Degree Status: Completed
2021/6 Subspecialist in General Internal Medicine, Royal College of Physicians and Surgeons of
Canada
2021/5 Fellow of The Royal College of Physicians of Canada, Royal College of Physicians and
Surgeons of Canada
2020/9 Specialist Physician in Internal Medicine, Royal College of Physicians and Surgeons of
Canada
2012/7 – 2016/6 Doctor of Medicine (M.D.), Université Laval
2008/7 – 2013/2 Doctor of Philosophy (Ph.D.): Cardiovascular Biochemistry, McGill University
2006/6 – 2008/7 Master of Science (M.Sc.): Biochemistry and Human Genetics, McGill University
2003/6 – 2006/7 Bachelor of Science (B.Sc.): Biochemistry, McGill University
2025/6 American Society for Preventive Cardiology Scholarship Program Awardee – selected from
60 applicants
American Society for Preventive Cardiology (ASPC)
Prize / Award
2025/3 First-author manuscript recognized as a Top 5 Most-Read Article in JACC: Advances
for 2024 Iatan I, Huang K, Vikulova D, Ranjan S, Brunham LR. Association of a Low-
Carbohydrate High-Fat Diet With Plasma Lipid Levels and Cardiovascular Risk.
Journal of the American College of Cardiology: Advances
Distinction
2024/4 Invited Speaker at the American College of Cardiology (ACC.24), Atlanta, Georgia. –
Debating Controversies in Cardiovascular Health
American College of Cardiology (ACC.24)
Distinction
2023/11 Clinical Science Winner – Trainee Research Award: Familial Hypercholesterolemia in
Canada: Investigating Management Patterns and Clinical Outcomes from the FH Canada
Registry
Canadian Cardiovascular Society / VASCULAR
Prize / Award
2023/3 – 2025/2 National Lipid Association Lipid Scholarship Program Awardee – selected as top 6 award
winners from 59 candidates worldwide
National Lipid Association
Prize / Award
Research Disciplines: Cardiology
2023/2 Travel Award
European Atherosclerosis Society
Prize / Award
Research Disciplines: Cardiology
2021/10 CIHR-supported Canadian Cardiovascular Congress Bursaries – selected as part of top 30
research abstracts
Canadian Cardiovascular Society
Prize / Award
2021/5 1st place Clinical Oral Presentation for the McGill McGregor Cardiovascular Research Day
The Research Institute of the McGill University Health Centre
Prize / Award
2019/10 General Internal Medicine Travel Scholarship – 500 (Canadian dollar)
McGill University Health Centre
Prize / Award
2017/11 Invited Speaker Travel Award at the 17th Annual Congress of the SSVQ – 750 (Canadian
dollar)
Société des Sciences Vasculaires du Québec (SSVQ)
Prize / Award
2017/11 Invited Speaker at the 17th Annual Congress of the SSVQ
Société des Sciences Vasculaires du Québec (SSVQ)
Distinction
2013/5 Junior Investigator Award for Women – 1,000 (United States dollar)
American Heart Association
Prize / Award
2012/5 Best Graduate Student Poster Presentation – 1,000 (Canadian dollar)
Cardiovascular Research Day, McGill University
Prize / Award
2011/11 Best Graduate Student Oral Presentation Award – 500 (Canadian dollar)
National Canadian Lipoprotein Conference
Prize / Award
2010/9 – 2009/9 Departmental Principal Graduate Fellowship in Biochemistry – 2,500 (Canadian dollar)
McGill University
Prize / Award
2010/5 Invited Guest Speaker
International Atherosclerosis Society
Distinction
2010/5 Graduate Trainee Presentation Award – 1,000 (Canadian dollar)
International Atherosclerosis Society
Prize / Award
2010/5 Student Travel Award – 1,000 (Canadian dollar)
International Atherosclerosis Society
Prize / Award
2009/2 Dean’s Honour List – Master of Science
McGill University
Distinction
2008/10 Best Graduate Student Poster Award – 1,000 (Canadian dollar)
National Canadian Lipoprotein Conference
Prize / Award
2007/10 – 2007/12 McKinnell Student Travel Award – Biochemistry – 1,000 (Canadian dollar)
McGill University
Prize / Award
2007/3 McGill Viewbook Science Citation
McGill University
Citation
2003/6 Dean’s Honour List – Health Science
Marianopolis College
Distinction
2024/3 Assistant Professor – General Internal Medicine
General Internal Medicine, Medicine, McGill University Health Centre
2024/3 Co-Principal Investigator
FH Canada Registry
2024/3 Co-Principal Investigator
Canadian Lipoprotein(a) [Lp(a)] Registry
2022/12 Co-Investigator – Pan-Canadian Clinical Trials
General Internal Medicine, Medicine, ARC Biosystems
2021/11 Board Member – Canadian Hypertension Specialists Society
University of British Columbia
2023/7 – 2024/2 Attending Physician – Vascular Medicine Clinic
General Internal Medicine, Medicine, St. Paul’s Hospital
2022/6 – 2024/2 Attending Physician – General Internal Medicine Division
General Internal Medicine, Medicine, University of British Columbia
2021/11 – 2023/12 Reviewer – University of British Columbia Medical Journal
University of British Columbia
2021/9 – 2022/12 Postdoctoral Fellow in Cardiovascular Disease Prevention, Cardiometabolic Health and
Clinical Lipidology
General Internal Medicine, Medicine, University of British Columbia
2008/5 – 2013/9 Teaching Assistant
Biochemistry, Medicine, The Research Institute of the McGill University Health Centre
2001/8 – 2008/8 Academic Tutor
Health Science, Medicine, Marianopolis College
2005/5 – 2005/8 Research Assistant
Biochemistry, The Research Institute of the McGill University Health Centre, Cancer
Research Laboratory
The primary affiliation is denoted by (*)
(*) 2024/3 Assistant Professor – Clinician Investigator, General Internal Medicine Division, Medicine,
McGill University
2023/1 Clinician Investigator – Centre for Heart Lung Innovation, Providence Health Care, St.
Paul’s Hospital, Medicine, University of British Columbia
1. (2025). L’hypercholestérolémie familiale au Canada: perspectives du registre national et implications
cardiovasculaires. 19ᵉ Congrès de la Nouvelle Société Francophone d’Athérosclérose – 18-20 June 2025,
France
Main Audience: Researcher
Invited?: Yes
2. (2025). Génétique, lipides et risque cardiovasculaire: le rôle de l’hypercholestérolémie familiale et de la
lipoprotéine(a) dans les cohortes canadiennes. Cardiology Grand Rounds – Laval University, Quebec,
Canada
Main Audience: Researcher
Invited?: Yes
3. (2025). The patient with elevated Lp(a): What to do?. 16th Annual State of the Heart Symposium 2025 –
Collaborative CME and Research Network – June 11 2025, Canada
Main Audience: General Public
Invited?: Yes
4. (2025). CCS Secondary Prevention Pathway: Establishing Standards for Long-Term Post-Acute Coronary
Syndrome Care. Canadian Cardiovascular Society CME-accredited Webinar, Canada
Main Audience: General Public
Invited?: Yes
5. (2024). Sex Differences in the Treatment of Familial Hypercholesterolemia: A Systematic Review and Metaanalysis.
92nd European Atherosclerosis Society Congress, France
Main Audience: Knowledge User
Invited?: Yes
6. (2024). Stratification du risque et prise en charge au-delà du C-LDL. Webinar – Association des
Cardiologues du Québec (CME-accredited), Canada
Main Audience: General Public
Invited?: Yes
7. (2024). Debating Controversies in Cardiovascular Health – Does a Very Low-Carbohydrate Diet Have
a Role in my Cardiovascular Practice? Extreme Makeover, Diet Edition – Debating Controversies in
Cardiovascular Health. American College of Cardiology (ACC.24), Atlanta, United States of America
Main Audience: Researcher
Invited?: Yes
8. (2024). Management of Dyslipidemia – Coronary Artery Calcium Scoring and Lipoprotein(a) in Risk
Assessment. Canadian Cardiovascular Society, Montreal, Canada
Main Audience: Knowledge User
Invited?: Yes
9. (2024). The Bad, the Good, and the New: LDL, HDL, sex, and new tricks. Cardiology Grand Rounds –
McGill University, Montreal, Canada
Main Audience: Researcher
Invited?: Yes
10. (2024). Lp(a): A Small Particle with a Large Impact – 10 Things You Need to Know About This Hidden,
Inherited, Independent Risk Factor. Accredited Symposium – Canadian Cardiovascular Congress (CCC
2024), Vancouver, Canada
Main Audience: Researcher
Invited?: Yes
11. (2024). Low-Carbohydrate Diets and Cardiovascular Health: Weighing the Benefits and the Risks.
Cardiology Grand Rounds – UBC Division of Cardiology, Vancouver, Canada
Main Audience: Researcher
Invited?: Yes
12. (2023). European Atherosclerosis Society Canadian Lipoprotein(a) Consensus. European Atherosclerosis
Society Lipid Clinic Network, Canada
Main Audience: Knowledge User
Invited?: Yes
13. (2023). Familial Hypercholesterolemia in Canada: Investigating Management Patterns and Clinical
Outcomes from the FH Canada Registry (ORAL). VASCULAR 2023, Canada
Main Audience: Researcher
Invited?: Yes
14. (2023). Lipoprotein(a): why does it matter?. VASCULAR 2023, Canada
Main Audience: Researcher
Invited?: Yes
15. (2023). Genetic Lipid Disorders and Premature Atherosclerotic Cardiovascular Disease: Current and
Emerging Strategies for Diagnosis and Treatment. VASCULAR 2023, Canada
Main Audience: Researcher
Invited?: No
16. (2023). Association of a Low-Carbohydrate High-Fat (Ketogenic) Diet with Plasma Lipid Levels and
Cardiovascular Risk in a Population-Based Cohort (ORAL). American College of Cardiology / World
Congress of Cardiology (ACC.23/WCC) – Late-Breaking Clinical Trials – Featured Clinical Research II
session, New Orleans, United States of America
Main Audience: Researcher
Invited?: Yes
17. (2023). Hot Topics in Internal Medicine – Why You Should Order Lipoprotein(a) on Everyone. University of
British Columbia Continuing Professional Development, Faculty of Medicine, Vancouver, Canada
Main Audience: General Public
Invited?: Yes
18. (2023). Premature Atherosclerotic Cardiovascular Disease during a Low-carbohydrate High-fat Diet: A
Case Series (POSTER). University of British Columbia Faculty of Medicine Precision Health Symposium,
Vancouver, Canada
Main Audience: Researcher
Invited?: No
19. (2023). Familial Hypercholesterolemia in Canada: Investigating Management Patterns and Clinical
Outcomes from the FH Canada Registry (ORAL). 91st European Atherosclerosis Society Congress,
Mannheim, Germany
Main Audience: Researcher
Invited?: Yes
20. (2022). Sex Disparities in Treatment and Clinical Outcomes of Familial Hypercholesterolemia (POSTER).
Canadian Cardiovascular Congress, Ottawa, Canada
Main Audience: Researcher
Invited?: No
21. (2022). A Single Center Experience with the Only Clinically Validated Genetic Screening for Familial
Hypercholesterolemia in Canada: A Retrospective Cohort Study (POSTER). National Lipid Association
Scientific Sessions, Scottsdale, Arizona, United States of America
Main Audience: Researcher
Invited?: No
22. (2022). Familial hypercholesterolemia in Canada: Investigating management patterns and clinical outcomes
from the FH Canada Registry (ORAL). Canadian Lipid and Vascular Summit, Whistler, Canada
Main Audience: Researcher
Invited?: Yes
23. (2022). Possible New Channelopathy Associated with Elevated Aldosterone Levels (ORAL). 29th Scientific
Meeting of the International Society of Hypertension, Kyoto, Japan
Main Audience: Researcher
Invited?: Yes
24. (2022). Familial Hypercholesterolemia – Family Care and Women’s Health (ORAL). 2022 British Columbia
Patient Engagement Forum on Familial Hypercholesterolemia, Vancouver, Canada
Main Audience: General Public
Invited?: Yes
25. (2022). A Clinically Validated Genetic Screening for Familial Hypercholesterolemia in Québec (ORAL).
McGill Maurice McGregor Cardiovascular Research Day, Montreal, Canada
Main Audience: Researcher
Invited?: No
26. (2021). A Clinically Validated Genetic Screening for Familial Hypercholesterolemia in Québec (VIRTUAL
POSTER). Canadian Cardiovascular Congress, Canada
Main Audience: Researcher
Invited?: No
27. (2020). Is Maternal Lipid Profile in Early Pregnancy Associated with Pregnancy Complications and Blood
Pressure in Pregnancy and Long Term Postpartum? (ORAL). As part of one of my elective rotations at
Université de Montréal, I was selected to present a journal club on lipid disorders in pregnancy and long
term outcomes. This talk was presented in front of the Medical Obstetrical group., Montreal, Canada
Main Audience: General Public
Invited?: No
2023/03/07 ‘Keto-like’ diet may be associated with a higher risk of heart disease, CNN Newsroom,
CNN
2023/03/10 Does a Low-carb, High-fat Diet Increase Your Risk of Heart Disease?, Daily Scan
2023/03/06 ‘Keto-like’ diet may be associated with a higher risk of heart disease, CTV News
2023/03/05 ‘Keto-Like’ Diet May Be Linked to Higher Risk of Heart Disease, Cardiac Events, American
College of Cardiology
Journal Articles
1. Choi HY, Ruel I, Choi S, Iatan I, Choi S, Lee JY, Genest J. (2025). Low-Dose Docetaxel Is Effective in
Reducing Atherogenic Lipids and Atherosclerosis. Int J Mol Sci. 26(4): 1484.
Published
Refereed?: Yes
2. Iatan I, Koschinsky ML, Trenaman L, Zhang W, Thanassoulis G, Brunham LR, Mancini GBJ, Francis
GA. (2025). Rationale for the Routine Screening of Lipoprotein (a) in Cardiovascular Risk Assessment.
European Journal of Preventive Cardiology. 32: zwaf342.
First Listed Author
Published
Refereed?: Yes
3. Marinho LL, Ribeiro ML, Lawler PR, Iatan I, Godoy LC, Rached FH, Maranhão RC. (2025). Impact of
Selective Peroxisome Proliferator-Activated Receptor (PPAR)-α Modulators and Fibrates on Microvascular
Disease: Is There Still Room?. Curr Atheroscler Rep. 27(1): 1-14.
Co-Author
Published
Refereed?: Yes
4. Mancini GBJ, Ryomoto A, Yeoh E, Iatan I, Brunham LR, Hegele RA. (2025). Reappraisal of statin primary
prevention trials: implications for identification of the statin-eligible primary prevention patient. Eur J Prev
Cardiol. N/A: N/A.
In Press
Refereed?: Yes
5. Mulder JWCM, Reijman MD, Kusters DM, Boersma E, Alnouri F, Blom DJ, Catapano AL, Cuchel M, Dann
EJ, Freiberger T, Groselj U, Harada-Shiba M, Hovingh GK, Iatan I, Ibarretxe D, Kayikcioglu M, Kim NT,
Klingel R, Raal FJ, Reeskamp LF, Sadiq F, Schonck WAM, Tromp TR, Truong TH, Wiegman A, Roeters
van Lennep JE. (2025). Homozygous Familial Hypercholesterolemia International Clinical Collaborators.
Homozygous Familial Hypercholesterolemia Is a Life-Limiting Condition: Medical Life-Trajectories in the
Post-2010 Era. JACC: Journal of the American College of Cardiology. 85(19): 1898-1903.
Co-Author
Published
Refereed?: Yes
6. Kramer AI, Iatan I, Brunham LR. (2025). The need for national and international registries of patients with
elevated lipoprotein(a). Curr Opin Lipidol. 36(3): 105-110.
Co-Author
Published
Refereed?: Yes
7. Iatan I, Akioyamen LE, Ruel I, Guerin A, Hales L, Coutinho T, Brunham LR, Genest J. (2024). Sex
differences in treatment of familial hypercholesterolaemia: a meta-analysis. Eur Heart J. 45(35): 3231-3250.
First Listed Author
Published
Refereed?: Yes
8. European Atherosclerosis Society Familial Hypercholesterolaemia Studies Collaboration (EAS FHSC).
(2024). Association of BMI, lipid-lowering medication, and age with prevalence of type 2 diabetes in adults
with heterozygous familial hypercholesterolaemia: a worldwide cross-sectional study. Lancet Diabetes
Endocrinol. 12(11): 811-823.
Published
Refereed?: Yes
9. Iatan I, Huang K, Vikulova D, Ranjan S, Brunham LR. (2024). Association of a Low-carbohydrate High-fat
Diet with Lipid Levels and Cardiovascular Risk. JACC Advances. 3(6): 1-14.
First Listed Author
Published
Refereed?: Yes
10. Paquette M, Ruel I, Guay SP, Al-Baldawi Z, Brisson D, Gaudet D, Couture P, Bergeron J, Hegele RA,
Francis GA, Sherman MH, McPherson R, Ransom T, Brunham LR, Mancini GJ, McCrindle BW, Iatan I,
Genest J, Baass A. (2024). Extreme LDL-C concentration is associated with increased cardiovascular
disease in women with homozygous familial hypercholesterolemia. J Clin Lipidol. N/A: N/A.
In Press
Refereed?: Yes
11. Alshibani B, Iatan I, Guerin A, Ruel I, Cermakova L, Ramanakumar AV, Pilote L, Coutinho T, Brunham LR,
Genest J. (2024). Sex differences in the perception of cardiovascular risk in familial hypercholesterolemia. J
Clin Lipidol. 18(1): e97-e104.
Co-Author
Published
Refereed?: Yes
12. Al-Baldawi Z, Brown L, Ruel I, Baass A, Bergeron J, Cermakova L, Couture P, Gaudet D, Francis GA,
Hegele RA, Iatan I, Mancini GBJ, McCrindle BW, Ransom T, Sherman MH, McPherson R, Genest J,
Brunham LR. (2024). Sex Differences in the Presentation, Treatment and Outcomes of Patients with
Homozygous Familial Hypercholesterolemia. J Clin Lipidol. 18(7): 14.
Co-Author
Published
Refereed?: Yes
13. Iatan I, Mancini GBJ, Yeoh E, Hegele RA. (2023). Statin associated muscle symptoms (SAMS): strategies
for prevention,assessment and management. Expert Rev Cardiovasc Ther. 21(6): 423-435.
First Listed Author
Published
Refereed?: Yes
14. Mancini GBJ, Ryomoto A, Iatan I, Hegele RA. (2023). LDL-C Estimation Equation Performance
Characteristics Highlight Value of Preferentially Using Non-HDL Cholesterol or Directly Measured
Apolipoprotein B. Can J Cardiol. 39(7): 963-966.
Co-Author
Published
Refereed?: Yes
15. Choi HY, Iatan I, Ruel I, Brown L, Hales L, Choi, S, Genest J. (2023). Docetaxel as a Model Compound
to Promote HDL (High-Density Lipoprotein) Biogenesis and Reduce Atherosclerosis. Arterioscler Thromb
Vasc Biol. 43(5): 609-617.
Co-Author
Published
Refereed?: Yes
16. Choi HY, Choi S, Iatan I, Ruel I, Genest J. (2023). Biomedical Advances in ABCA1 Transporter: From
Bench to Bedside. Biomedicines. 11(2): 1-14.
Co-Author
Published
Refereed?: Yes
17. Iatan I, Guan M, Humphries KH, Yeoh E, Mancini GBJ. (2023). Atherosclerotic coronary plaque regression
and decreased risk of adverse cardiovascular events: an updated meta-regression analysis. JAMA
Cardiology. 8(10): 937-945.
First Listed Author
Published
Refereed?: Yes
18. Brown L, Ruel I, Baass A, Bergeron J, Brunham LR, Cermakova L, Couture P, Gaudet D, Francis GA,
Hegele RA, Iatan I, Mancini GBJ, McCrindle B, Ransom T, Sherman MH, McPherson R, Genest J. (2023).
Homozygous Familial Hypercholesterolemia in Canada: An Observational Study. JACC Advances. 2(3):
1-13.
Co-Author
Published
Refereed?: Yes
19. Guerin A, Iatan I, Ruel I, Ngufor LF, Genest J. (2023). Genetic testing for familial hypercholesterolemia in
Quebec, Canada: a single-centre retrospective cohort study. CMAJ Open. 11(4): E754-E764.
Co-Author
Published
Refereed?: Yes
20. Brown L, Ruel I, Baass A, Bergeron J, Brunham LR, Cermakova L, Couture P, Gaudet D, Francis GA,
Hegele RA, Iatan I, Mancini GBJ, McCrindle B, Ransom T, Sherman MH, McPherson R, Genest J. (2023).
Design, Rationale and Preliminary Results of the Canadian Homozygous FH Registry (2008-2022 Update).
Can J Health Technol. 3(2): 1-12.
Co-Author
Published
Refereed?: Yes
21. Iatan I, Choi HY, Genest J. (2022). HDL and Cardiovascular Disease – Where Do We Stand? Chapter 6
in Lipids: Update on Diagnosis and Management of Dyslipidemia.Endocrinology and Metabolism Clinics of
North America. Elsevier. 51(3): 557-572.
First Listed Author
Published
Refereed?: Yes
22. Iatan I, Lee TC, McDonald EG. (2021). Tenofovir-induced osteomalacia with hypophosphatemia. British
Medical Journal (BMJ) Case Reports. 14(5): e240387.
First Listed Author
Published
Refereed?: Yes
Book Chapters
1. Iatan I, Choi HY, Genest J. (2021). High-Density Lipoprotein and Cardiovascular Disease – Where Do We
Stand?. Lipids: Update on Diagnosis and Management of Dyslipidemia. (51(3))
First Listed Author
Published, Endocrinology and Metabolism Clinics of North America. Elsevier
Refereed?: Yes